AMOXTIN-PHARMA

The combination of amoxycillin and colistin acts additive. Amoxycillin is a semisynthetic broadspectrum
penicillin with a bactericidal action against both Gram-positive and Gram-negative bacteria. The spectrum
of amoxycillin includes Campylobacter, Clostridium, Corynebacterium, E. coli, Erysipelothrix, Haemophilus,
Pasteurella, Salmonella, penicillinase-negative Staphylococcus and Streptococcus, spp. The bactericidal
action is due to inhibition of cell wall synthesis.
Amoxicillin is mainly excreted in urine. A major part can also be excreted in bile. Colistin is an
antibiotic from the group of polymyxins with a bactericidal action against Gram-negative
bacteria like E. coli, Haemophilus and Salmonella. Since colistin is absorbed for a very small
part after oral administration only gastrointestinal indications are relevant.